Alois Alzheimer †.

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From Alois to Amyvid: seeing Alzheimer disease.

Neurology 2012;79:1628–1629 When Alois Alzheimer first described the neuropathologic hallmarks of his eponymous disease (Alzheimer disease [AD]) in 1906,1 the possibility of detecting amyloid plaques in vivo was unimaginable. About a century later, this became a reality when Klunk and colleagues2 demonstrated that the C-labeled PET tracer Pittsburgh compound B (PiB) selectively bound to fibrill...

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Alois Alzheimer is best known for his description of neurofibrillary changes in brain neurons of a demented patient, identifying a novel disease, soon named after him by Kraepelin. However, the range of his studies was broad, including vascular brain diseases, published between 1894 and 1902. Alzheimer described the clinical picture of Arteriosclerotic atrophy of the brain, differentiating it f...

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The familiar term "Alzheimer's disease" was coined by Emil Kraepelin to honour his pupil, Alois Alzheimer. However, little is known about the life of the man after whom this important and well-known disease was termed. On the centennial of the discovery of Alzheimer's disease, it is appropriate to report some aspects of the life and scientific work of Alois Alzheimer. The authors contacted all ...

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ژورنال

عنوان ژورنال: European Neurology

سال: 1916

ISSN: 0014-3022,1421-9913

DOI: 10.1159/000190919